Calcifying Fibrous Tumor Mimicking Pancreatic Cancer

We report a case of a 75-year-old male incidentally diagnosed with pancreatic mass. A laparoscopic radical antegrade posterior modular pancreatosplenectomy was performed. An unexpected diagnostic of calcifying fibrous tumor (CFT) was revealed. CFT can mimic malignancy due to its imaging characteristics, location and growth and it should be taken into consideration in the differential diagnosis when pancreatic malignancy is suspected. Most of them are asymptomatic tumors discovered in imaging performed for other reasons. In some cases, it presents non-specific symptoms. It can also debut with systemic symptoms. The radiological characteristics of this tumor are unspecific and usually do not provide a definitive diagnosis. Usually, the definitive diagnosis is given by histopathology, where immunohistochemistry techniques are very useful. No deaths have been reported from this cause, however, there are a few cases of local recurrence described in the literature. Although the optimal follow-up time for the CFT is not known, if free margins are achieved, no lymph nodes or metastasis are expected to appear in the follow-up.