Impact of Bariatric Surgery in A Cohort of Patients with Type 2 Diabetes and Obesity

1. Abstract 

1.1. Aims: To evaluate the metabolic effects of Bariatric Surgery (BS) and bone mineral metabolism changes after BS in a population of obese diabetic patients. 

1.2. Materials and Methods: 56 patients were evaluated before and after undergoing BS. Personal background, anthropometric measurements, blood pressure, body mass index (BMI), hemogram, liver panel, glycemia, 25-OH-Vitamin-D, lipid profile, HbA1c, renal function, and calcium, phosphorus, magnesium, creatinine, and ionogram in plasma and 24-hs urine were analyzed. 

1.3. Results: BMI decreased between preoperative and postoperative periods (p<0,0001). There were no significant differences in blood pressure. Regarding metabolic parameters, significant differences were observed for glycemia, HbA1c, triglycerides (TG), TG/HDL, HDL, and uric acid. Hypoglycemia and anemia were found in 3, 5% and 14, 28% of patients post BS, respectively. There was a statistically significant reduction between pre and post BS levels for serum calcium, magnesium, sodium and creatinine, and a statistically significant increase between pre and post BS levels for 25-OH-Vitamin-D, serum and urinary phosphate, and urinary creatine