Meckel’s diverticulum is the most common congenital defect of the gastrointestinal tract, caused by an incomplete obliteration of ductus omphaloentericus (yolk sac) during intrauterine life. Given that the ductus omphaloentericus contains pluripotent cells during the intrauterine life, the diverticular mucosa may contain cell islets of different types of tissues, such as gastric and intestinal mucosa, pancreatic cells and others. However, the occurrence of neuroendocrine tumours in Meckel’s diverticulum is very rare. Causes ileus, besides its tumorous tissue, are fibrous changes in mesentery induced by the neuroendocrine tumour as well.
The paper presents a case of a 48-year-old patient with an acute abdomen, caused by perforation of Meckel’s diverticulum. Histological examination has revealed the presence of a neuroendocrine tumour spreading across muscularis propria and incipient spread into subserosa.