Experimental Analysis of Tear Fluid and their Processing for the Diagnosis of Multiple Sclerosis

1. Abstract
A pilot analysis of the tear fluid of patients with multiple sclerosis (MS) collected by glass microcapillary was performed using various experimental methods: liquid chromatography-mass spectrometry, Raman spectroscopy, infrared spectroscopy, and atomic force microscopy. Infrared spectroscopy found no significant difference in both MS patients and control spectra of tear fluid; all three significant peaks were located at around the same position.